Effect of Dual-task Training on Mobility Function in Patients with Parkinson’s Disease
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摘要:
目的 检验双重任务训练对帕金森患者运动功能的影响。 方法 56名帕金森患者随机分为实验组和对照组。每组患者接受为期2周，每周5次，每次60 min的训练，并比较2组患者训练前后的运动和认知功能。 结果 尽管2组患者完成10 m步行和起立行走计时（TUG）测试的时间变化值无显著差异（P > 0.05），但仅有实验组在双重任务状态下改善显著（ P < 0.05）。对于简易平衡评定系统测试和特定活动平衡信心量表，仅有实验组呈现出显著的时间效应。 结论 双重任务训练对帕金森患者步行速度和平衡功能具有改善趋势。未来的研究应该探索改善帕金森病患者运动功能的最佳训练方案，以及将获得的能力转移到其他新的双重任务场景的问题。 -
关键词:
- 帕金森病 /
- 双重任务 /
- 步行能力 /
- 平衡功能 /
- 随机对照试验
Abstract:Objective To examine the effect of dual-task （DT） training on mobility function in patients with Parkinson’s disease （PD）. Methods 56 patients with PD were randomly divided into DT training group or single-task （ST） training group. Each group of patients received the 60 min/session training, 5 times/week, for over 2 weeks. The motor and cognitive functions of the two groups were compared before and after the training. Results Although there was no significant difference between the two groups in the change time taken to complete the 10 m walking and timed up and go （TUG） test under either DT or ST condition, only the experimental group improved significantly under DT condition （P < 0.05）. For balance function （mini-balance evaluation system test, Mini-BESTest） and balance efficiency （activity-specific balance confidence scale, ABC）, only DT training group showed the significant time effect. Conclusion Walking speed and balance function in patients with PD tend to be improved after DT training. Future research should be conducted to explore the optimized training protocol and improve DT motor function in patients with PD and the ability of transferring the acquired function to new DT scenarios. -
Key words:
- Parkinson’s disease /
- Dual task /
- Walking ability /
- Balance function /
- Randomized controlled trial
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图 1 筛选流程图
Figure 1. Flow chart
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图 2 干预前后2组Mini-BESTest、ABC、MoCA分数比较
Figure 2. Comparison of the scores of Mini-BESTest、ABC、MoCA between the two groups before and after intervention
A：2组受试者训练前后Mini-BESTest分数；B：2组受试者训练前后ABC分数；C：2组受试者训练前后MoCA分数。*P < 0.05。
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表 1 人口学特征[（
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